Beclomethasone at different doses for chronic asthma

Beclomethasone in childhood asthma.

It has not been possible so far to produce a systemic corticosteroid with anti-inflammatory effect on local tissues and without glucocorticoid action. However, esterification of the potent antiinflammatory steroid betamethasone with valeric acid in the 17 carbon position produced betamethasone-17-valerate (Betnovate*), a steroid with marked topical anti-inflammatory activity. Beclomethasone dip...

Beclomethasone aerosol in childhood asthma.

Godfrey, S., and Konig, P. (1973). Archives of Disease in Childhood, 48, 665. Beclomethasone aerosol in childhood asthma. Twenty children have been treated with the steroid aerosol beclomethasone, half of them in an open trial and the other half in a controlled cross-over trial. Children were assessed by means of clinical examination, diary records, and twice-daily peak flow rate measurements m...

Substitution of beclomethasone aerosol for oral prednisolone in the treatment of chronic asthma.

In a double-blind study 10 patients with chronic asthma received beclomethasone dipropionate 400 mug daily in a Freon propellant from a pressurized dispenser, and 10 patients received the Freon propellant alone. At the start of the trial each patient was receiving long-term maintenance treatment with oral prednisolone in a dose of 7.5 to 15 mg daily. The daily dose of prednisolone was reduced b...

Beclomethasone dipropionate aerosol in childhood asthma.

Beclomethasone and albuterol in mild asthma.